ROBUST ENZYMES OPTIMIZED FOR CONSISTENT, SCALABLE RNA MANUFACTURING.
The Prima RNApols® portfolio includes purpose-built RNA polymerases engineered to improve IVT performance across diverse RNA manufacturing workflows. Prima RNApols® support cleaner, higher-quality, lower-cost RNA production from R&D through process development and scale-up.
Key strengthStrongSupported✕Not compatible–Data coming soon
CAPPING
AG CAP ANALOG
AU CAP ANALOG
RNA YIELD
ACROSS DIVERSE
TEMPLATES
TEMPLATES
dsRNA
dsRNA REDUCTION
vs. conventional T7
COST SAVINGS
REAGENT EFFICIENCY
TRANSLATABILITY
PROTEIN EXPRESSION
PROMOTER
T7 PROMOTER
COMPATIBLE no redesign required
COMPATIBLE no redesign required
Key Strength
Strong
Supported
✕
Not Compatible
Key strengthStrongSupported✕Not compatible–Data coming soonPRIMA CAP AU
AU-capped RNA & saRNA
CAPPING
AG CAP ANALOG
AG CAP ANALOG
AU CAP ANALOG
RNA YIELD
ACROSS DIVERSE
TEMPLATES
ACROSS DIVERSE
TEMPLATES
dsRNA
dsRNA REDUCTION
vs. conventional T7
dsRNA REDUCTION
vs. conventional T7
COST SAVINGS
REAGENT EFFICIENCY
REAGENT EFFICIENCY
TRANSLATABILITY
PROTEIN EXPRESSION
PROTEIN EXPRESSION
–
PROMOTER
T7 PROMOTER COMPATIBLE
no redesign required
T7 PROMOTER COMPATIBLE
no redesign required
✕
1
RUO KITS TODAY. ESTABLISHED CAPABILITIES TO SUPPORT YOUR GMP MANUFACTURING AS PROGRAMS ADVANCE.
Prima RNApols® support R&D, screening, and process-development workflows. Primrose Bio has established manufacturing capabilities to produce GMP-grade RNA polymerases. As your programs advance toward clinical, or commercial manufacturing, we supply Prima RNApols through ISO 13485-certified quality systems, analytical capability and manufacturing infrastructure.